Search results “Depends on regulation”
Laurent Bourquin - The EU approach to crypto regulation depends on the USA
The European Union authorities’ final approach to the blockchain and cryptocurrency will be formed under the US influence, Admin of BitcoinFranceClub and COO of CoinStruction Laurent Bourquin believes
Views: 83 Crypto Market News
Population regulation | Ecology | Khan Academy
Learn the difference between density-dependent and density-independent factors that affect population growth, and explore examples of each. Watch the next lesson: https://www.khanacademy.org/science/biology/ecology/population-growth-and-regulation/v/predator-prey-cycle Missed the previous lesson? Watch here: https://www.khanacademy.org/science/biology/ecology/population-growth-and-regulation/v/exponential-and-logistic-growth-in-populations Ecology on Khan Academy: Why are polar bears found only in the Arctic? Why does mildew grow in your shower and not (hopefully) in your sock drawer? Learn how ecologists study the interactions between organisms and their environment, and how these interactions affect where, and in what numbers, different types of organisms are found. About Khan Academy: Khan Academy offers practice exercises, instructional videos, and a personalized learning dashboard that empower learners to study at their own pace in and outside of the classroom. We tackle math, science, computer programming, history, art history, economics, and more. Our math missions guide learners from kindergarten to calculus using state-of-the-art, adaptive technology that identifies strengths and learning gaps. We've also partnered with institutions like NASA, The Museum of Modern Art, The California Academy of Sciences, and MIT to offer specialized content. For free. For everyone. Forever. #YouCanLearnAnything Subscribe to KhanAcademy: https://www.youtube.com/subscription_center?add_user=khanacademy
Views: 49959 Khan Academy
Understand How Health is Depends by Body Regulation
I share my thoughts on why we need to understand health from a regulation perspective. In order to deal with chronic conditions, we need to start looking at health from a regulation perspective. Key topics : 1) Why do we need to regulate our bodies in order to survive? 2) How do we know when we are off-balance? 3) How well is our body regulating itself versus the external stimuli(stressors)?
Views: 7 Jen Sern
"Cryptocurrency Regulation Depends On Each Country" Datametrex's Jeff Stevens
subscribe: https://www.youtube.com/toddshapiroshow Todd Shapiro of the Todd Shapiro Show on SiriusXM Canada Laughs CH 168 sits down with Jeff Stevens from Datametrex (www.datametrex.com) to discuss the future of Cryptocurrency. Todd Shapiro on Twitter @ iamToddyTickles Listen weekdays from 4pm-6pm on SiriusXM Canada Laughs Ch.168! www.TheToddShapiroShow.com 1-87SXM-LAUGH DOWNLOAD THE PODCAST! https://itunes.apple.com/ca/podcast/the-todd-shapiro-show/id833625507?mt=2 LIKE OUR FACEBOOK PAGE! https://www.facebook.com/IamToddyTickles FOLLOW US ON TWITTER AND INSTAGRAM! www.Twitter.com/@ToddShapiroShow www.Instagram.com/ToddShapiroShow SUBSCRIBE ON YOUTUBE! https://www.youtube.com/channel/UCI1RHDoVjDdDMVcNW1rTxdA
Views: 13 ToddShapiroShow
Potassium Regulation: Potassium Secretion
This lesson explores the following: 1) Excretion of potassium depends on potassium secretion. 2) Potassium secretion occurs primarily along the collecting duct. 3) Apical potassium ion channels and the K/Cl cotransporter secrete potassium. 4) The negative-lumen potential influence potassium secretion 5) Luminal flow, luminal [Na+], and ENaC activity influence the driving forces Learn about Hypokalemia: http://aniveo.com/hypokalemia/ Test your knowledge on this lesson: http://aniveo.com/potassium-secretion/
Views: 11518 Lance Miller, PhD
CDKs, cyclines, cell cycle
This cell cycle regulation lecture explains about the role of CDK and cyclines in cell cycle. http://shomusbiology.com/ Download the study materials here- http://shomusbiology.com/bio-materials.html Cyclins were originally named because their concentration varies in a cyclical fashion during the cell cycle. (Note that the cyclins are now classified according to their conserved cyclin box structure, and not all these cyclins alter in level through the cell cycle.[2]) The oscillations of the cyclins, namely fluctuations in cyclin gene expression and destruction by the ubiquitin mediated proteasome pathway, induce oscillations in Cdk activity to drive the cell cycle. A cyclin forms a complex with Cdk, which begins to activate the Cdk, but the complete activation requires phosphorylation, as well. Complex formation results in activation of the Cdk active site. Cyclins themselves have no enzymatic activity but have binding sites for some substrates and target the Cdks to specific subcellular locations.[3] They were discovered by R. Timothy Hunt in 1982 while studying the cell cycle of sea urchins.[4][5] In an interview for the BBC4 documentary "The Life Scientific" (aired on 13/12/2011) hosted by Jim Al-Khalili, R. Timothy Hunt explained that the name "cyclin" was originally named after his hobby cycling. It was only after the naming did its importance in the cell cycle become apparent. As it was appropriate the name stuck.[6] R.Timothy Hunt: "By the way the name cyclin, which I coined, was really a joke, it's because I like cycling so much at the time but they did come and go in the cell..." [7] Cyclins, when bound with the dependent kinases, such as the p34 (cdc2) or cdk1 proteins, form the maturation-promoting factor. MPFs activate other proteins through phosphorylation. These phosphorylated proteins, in turn, are responsible for specific events during cycle division such as microtubule formation and chromatin remodeling. Cyclins can be divided into four classes based on their behavior in the cell cycle of vertebrate somatic cells and yeast cells: G1/S cyclins, S cyclins, M cyclins, G1 cyclins. This division is useful when talking about most cell cycles, but it is not universal as some cyclins have different functions or timing in different cell types. G1/S Cyclins rise in late G1 and fall in early S phase. The Cdk- G1/S cyclin complex begins to induce the initial processes of DNA replication, primarily by arresting systems that prevent S phase Cdk activity in G1. The cyclins also promote other activities to progress the cell cycle, like centrosome duplication in vertebrates or spindle pole body in yeast. The rise in presence of G1/S cyclins is paralleled by a rise in S cyclins. S cyclins bind to Cdk and the complex directly induces DNA replication. The levels of S cyclins remain high, not only throughout S phase, but through G2 and early mitosis as well to promote early events in mitosis. M cyclin concentrations rise as the cell begins to enter mitosis and the concentrations peak at metaphase. Cell changes in the cell cycle like the assembly of mitotic spindles and alignment of sister-chromatids along the spindles are induced by M cyclin- Cdk complexes. The destruction of M cyclins during metaphase and anaphase, after the Spindle Assembly Checkpoint is satisfied, causes the exit of mitosis and cytokinesis.[8] G1 cyclins do not behave like the other cyclins, in that the concentrations increase gradually (with no oscillation), throughout the cell cycle based on cell growth and the external growth-regulatory signals. The presence of G cyclins coordinate cell growth with the entry to a new cell cycle. Source of the article published in description is Wikipedia. I am sharing their material. © by original content developers of Wikipedia. Link- http://en.wikipedia.org/wiki/Main_Page Animation source: Discover Biology, Core 3rd Edition, W W Norton and company Link- http://www.wwnorton.com/college/biology/discoverbio3/core/content/index/animations.asp References- The cell: A molecular approach, fifth edition Geoffery M. Cooper and Robert E. Housman © ASM press and Sinauer Asociates, Inc.
Views: 166761 Shomu's Biology
How to practice emotional first aid | Guy Winch
We'll go to the doctor when we feel flu-ish or a nagging pain. So why don’t we see a health professional when we feel emotional pain: guilt, loss, loneliness? Too many of us deal with common psychological-health issues on our own, says Guy Winch. But we don’t have to. He makes a compelling case to practice emotional hygiene — taking care of our emotions, our minds, with the same diligence we take care of our bodies. TEDTalks is a daily video podcast of the best talks and performances from the TED Conference, where the world's leading thinkers and doers give the talk of their lives in 18 minutes (or less). Look for talks on Technology, Entertainment and Design -- plus science, business, global issues, the arts and much more. Find closed captions and translated subtitles in many languages at http://www.ted.com/talks/guy_winch_the_case_for_emotional_hygiene Follow TED news on Twitter: http://www.twitter.com/tednews Like TED on Facebook: https://www.facebook.com/TED Subscribe to our channel: http://www.youtube.com/user/TEDtalksDirector
Views: 1539889 TED
Road rules: pedestrians
Brush up on your road rule knowledge by viewing the top ten misunderstood road rules animations. The animations outline some of the rules the NSW community have said they need more clarification on, like mobile phone laws, roundabout rules and how and why we enforce in school zones. Road safety largely depends on road users being able to understand and follow the road rules, so share the animation links with your friends and colleagues and refresh your memory! For more information on road rules download the Top 10 misunderstood road rules in NSW guide (http://roadsafety.transport.nsw.gov.au/downloads/campaigns/top10_misunderstood.html) or visit http://roadsafety.transport.nsw.gov.au or http://www.rms.nsw.gov.au/ Like Us on Facebook: http://www.facebook.com/transportfornsw Follow Us on Twitter: http://www.twitter.com/transportfornsw See Us on Instagram: http://www.instagram.com/transportfornsw
Views: 156013 Transport For NSW
Lee Smolin: Physics Envy and Economic Theory
Economists were seduced by physics because it made their claims seem more scientific. Their belief was in the concept of equilibrium, in which it would be impossible to profit from trading around a circle of goods or a circle of currencies without actually producing anything. Of course, that is possible, and that did happen, and that's because you're never really at equilibrium. Transcript -- So I got pulled into economics in 2007 because of the 2008 economic crisis. Mike Brown who had been the first CFO of Microsoft, Chief Financial Officer of Microsoft and treasurer of Microsoft, he came to Toronto in 2007 and took my wife and I out to dinner and said he was trying to put together a research group to work on economics and he would like me to be involved. And I said, "I don't know anything about economics." And he said, "That's okay because nobody does and the whole system is about to collapse." He said, "The balance sheets of all the big investment banks -- it's like they have cancer. They're full of holes." And I remember being very struck by this because this was before anybody was talking about this. And so I started to meet with a group of people that he was pulling together to understand what was gonna happen and to understand if there was any way to save the situation. It was a very ambitious thing and, of course, we failed. But along the way I was motivated as a kind of public service to get interested in economics. And what I found . . . economics, in a way, is very easy for a physicist to understand because it's very mathematical. And the mathematical models that they use are very clean. They're based on assumptions and hypotheses, and you can study them. And as I studied it I began to understand, some for myself and more from just reading around because the faults with the standard economic models, with the standard models of finance, are well known. They have been in the literature for decades and decades. So let me give some examples. The standard model of economics is called the neoclassical model and it assumes that markets or systems where trading happens between consumers and firms and there's certain simple models of how that goes on. And the ideas that these come to equilibrium. Equilibrium not in the physical sense but in special economic sense in which you reach a point at which the prices are fixed such that market forces fix the prices such that you maximize the happiness of the consumers and maximize the profits of the firms. And in so called equilibrium nobody can become happier or more profitable without somebody else becoming less happy or less profitable. And the ideology behind this -- not behind the mathematics because mathematics doesn't have an ideology -- but behind the arguments that were made and still are made from this model is that markets don't need regulation because they have these natural equilibria where everybody benefits to the maximum possible. And if you're in equilibrium you can't do better. Now there's a fault with this and it's an obvious fault and it's been known since the 1970s from some theorems proved by some economists including some of the founders of this field of mathematical economics, which is that there's not one equilibrium, there are many equilibria. In fact, there's a vast number of equilibria. And so which equilibria, even assuming that this is a decent model of the economy which is not clear, but even assuming it's a good model, which equilibria you're in depends on the past history, it depends on regulation, it depends on politics, it depends on taste, it depends on changing taste, changing preferences. And so history matters and what's called path dependence matters. This takes us outside the neoclassical model of economics but it doesn't take us outside of economics because some wiser economist, for example, Brian Arthur had for years been developing models and theories of path dependent economy where the history does matter. People from the area of complex systems like Stu Kauffman, Prubac in developing models of markets where the history matters, where there's not a single equilibrium, where there are many equilibria. And where change is paramount. Another symptom of this is the idea that arbitrage isn't, I mean, in these neoclassical models when you go to equilibrium, arbitrage is impossible. Arbitrage is making a profit from trading around a circle of goods or a circle of currencies without actually producing anything. And in equilibrium that's supposed to be impossible but lots of firms and investment banks made fortunes off of currency trading, so why is that? It turns out because you're never really at equilibrium... Remainder of transcript: http://bigthink.com/videos/how-bad-science-led-to-the-economic-crisis Directed / Produced by Jonathan Fowler & Elizabeth Rodd
Views: 57487 Big Think
Can the Government Run the Economy?
With the smartest experts and the best economists, could the federal government run the U.S. economy? Could it keep America's $17 trillion economy going like a well-oiled machine? Steve Forbes, Chairman and Editor-in-Chief of Forbes Media, explains why no one person or group can "run" the economy, and why any attempt to do so can only make things worse. Donate today to PragerU! http://l.prageru.com/2ylo1Yt Joining PragerU is free! Sign up now to get all our videos as soon as they're released. http://prageru.com/signup Download Pragerpedia on your iPhone or Android! Thousands of sources and facts at your fingertips. iPhone: http://l.prageru.com/2dlsnbG Android: http://l.prageru.com/2dlsS5e Join Prager United to get new swag every quarter, exclusive early access to our videos, and an annual TownHall phone call with Dennis Prager! http://l.prageru.com/2c9n6ys Join PragerU's text list to have these videos, free merchandise giveaways and breaking announcements sent directly to your phone! https://optin.mobiniti.com/prageru Do you shop on Amazon? Click https://smile.amazon.com and a percentage of every Amazon purchase will be donated to PragerU. Same great products. Same low price. Shopping made meaningful. VISIT PragerU! https://www.prageru.com FOLLOW us! Facebook: https://www.facebook.com/prageru Twitter: https://twitter.com/prageru Instagram: https://instagram.com/prageru/ PragerU is on Snapchat! JOIN PragerFORCE! For Students: http://l.prageru.com/29SgPaX JOIN our Educators Network! http://l.prageru.com/2c8vsff Script: Is our economy a machine, like an automobile, a train or a power plant? One constantly hears phrases such as the economy “is overheating” or “needs to cool off” or “could use some stimulus.” These aren’t harmless metaphors. They epitomize how economists have taught us to see an economy—as something that can be manipulated, guided or driven. And guess who does the driving? The government. The government is supposed to make sure that the economy “hums” along at an even speed, going neither too fast nor too slow. But the economy is not a machine. It is made up of people, and no one can control what billions of them are going to do. What gets overlooked, underplayed or simply ignored is the extraordinary “churn” in the activities of a free market. New businesses open while others close, constantly. In the U.S. during normal times a half-million or more jobs are created each week, while another half-million are cut. Entrepreneurs continually roll out new products and services, most of which flop. But those that succeed can greatly improve our quality of life. What government can and should do is to positively influence the environment in which this hum of activity takes place through sensible taxation, monetary policy, government spending and regulation. And in almost all instances the best prescription for economic health is “less is more.” Catastrophic mistakes by governments can poison the marketplace, as happened during the Great Depression in the 1930s, to a lesser extent in the 1970s, and then again in the panic of 2008–09. The government’s recent mistakes have been compounded by tax increases and an avalanche of antigrowth regulations from ObamaCare, the Dodd-Frank financial services bill and all those Washington regulatory agencies, such as the FCC, the EPA and the National Labor Relations Board. If you want to understand why the American economy has been growing at the anemic pace of 1 to 2 percent a year, look no further. Again, the idea of an economy that purrs along like a well-oiled machine hurts, not enhances, wealth creation because invariably, it leads to growth retarding government intervention. Which brings us to bubbles. Shouldn’t the government, the argument goes, at least try to stop them from happening? Well, it depends. Those caused by misguided government policies like the housing bubble of the mid 2000’s, yes. Those caused by the free market, no. Bubbles have a bad name, but not all of them are created equal. There are healthy ones and unhealthy ones. The good kind develops when a lot of people simultaneously recognize a great opportunity. Computers are an excellent example. During the early 1980s there was a boom in personal computers–followed by a severe shakeout, when companies such as Atari and Commodore bit the dust. In the late 1990s a number of companies recognized the importance of search engines. Google emerged supreme with Microsoft and others relegated to fractional market shares. For the complete script, visit https://www.prageru.com/videos/can-government-run-economy
Views: 933823 PragerU
US Economic Recovery Depends on Global Recovery – Lael Brainard
This is a clip from the CGD event "Voices of Experience: A Conversation with Former Treasury Under Secretaries for International Affairs." Learn more and watch the full event at https://www.cgdev.org/event/voices-experience-conversation-former-treasury-under-secretaries-international-affairs
10 Must Not Do in Malaysia
Open below to see details from my video :) DO Pause the video to read the details if the Slide information is too fast. Coming to Malaysia for Holiday or Vacation? Here are some tips about What not to Do in Malaysia, 10 things not to do in Malaysia on your holiday vacation to ruin your holiday here. Malaysia is a high muslim populated country therefore there are certain rules and law to abide to when you are in Malaysia. These things not to do in Malaysia is just a precaution and warning for those whom have no expectations about Malaysia and being their First time to Malaysia. Malaysia is a multicultural country and you will need to respect all kinds of different culture here of different religion basis. However, all these must not do is not obligated for you to follow as is all depends on the type of people you meet throughout Malaysia due to the different culture and different religion. To All tourist, Welcome to Malaysia and to all Malaysians, if I ever wrote anything you disagree with and I believe there will be some disagreements, do let me know. If you have anything to add in, do comment down here so tourist would know when they visit Malaysia. Or just comment to say Where are you from ! I would be curious to know ! Have a nice stay in Malaysia. ► Please SUBSCRIBE https://www.youtube.com/feliciazoe90 Please THUMBS UP if you liked the video :) ♥My Other Social Network Links♥ Blog: http://www.feliciazoe.com Instagram: http://instagram.com/feliciazoe Twitter: Twitter: https://twitter.com/feliciazoe90 Facebook: http://www.facebook.com/Feliciazoe.my Business Email ONLY: [email protected] About Feliciazoe: https://youtu.be/0GlRPQtVn7w ———————Watch my recent videos————————— How to cut open Durian https://youtu.be/xLBrO9uQosQ Easy Travel Korean Language https://www.youtube.com/watch?v=5IeKoCtCwxA Learn Travel Malay Language https://www.youtube.com/watch?v=Yev7GllEhxY Learn Travel Chinese Language https://www.youtube.com/watch?v=cKL7YHtStcg Dont forget to check out Malaysian upcoming rising stars MGAG: Ever wondered what your favorite hit songs sound like in Bahasa Malaysia? So Check out their Hit Songs in Bahasa Malay and its super funny and entertaining !! https://www.youtube.com/watch?v=QDuv4Dp5u48
Views: 502366 Felicia zoe
Road rules: roundabouts
Brush up on your road rule knowledge by viewing the top ten misunderstood road rules animations. The animations outline some of the rules the NSW community have said they need more clarification on, like mobile phone laws, roundabout rules and how and why we enforce in school zones. Road safety largely depends on road users being able to understand and follow the road rules, so share the animation links with your friends and colleagues and refresh your memory! For more information on road rules download the Top 10 misunderstood road rules in NSW guide (http://roadsafety.transport.nsw.gov.au/downloads/campaigns/top10_misunderstood.html) or visit http://roadsafety.transport.nsw.gov.au or http://www.rms.nsw.gov.au/ Read Our blog: http://www.trippr.info Like Us on Facebook: http://www.facebook.com/transportfornsw Follow Us on Twitter: http://www.twitter.com/transportfornsw See Us on Instagram: http://www.instagram.com/transportfornsw
Views: 1601003 Transport For NSW
Regulation, Discretion, and Public Choice with Stephen M. Jones
This podcast episode was originally posted on February 24th, 2017. What follows is an edited partial transcript of my conversation with Stephen M. Jones. He is an economist for the US Coast Guard. However, we are discussing his own research, so nothing in this conversation should be taken to represent the official views of the US Coast Guard. Petersen: So Stephen, let’s start just by defining regulatory discretion. What does that mean in this context? Jones: Sure. So, I think first off, we should probably define regulation because when Congress writes a law, they pass the law on to regulatory agencies and it will say something to the effect of “agencies: issue a regulation.” So, when we talk about regulations this point isn’t always clear because people just aren’t familiar with this process. The regulation is a statement that kind of clarifies existing congressional law or is written in direct response to congressional law. And this could be as specific as, say, Congress can direct an agency to set an exact amount of pollution that is permitted for an industry to as broad as saying something like “protect consumers from unreasonable risks.” And then the agency has room to interpret that statement as wide as it wants to. So, when I talk about agency discretion what I’m really talking about is Congress wrote a rule that gave the agency power to issue legally binding rules that may or may not trace directly back to Congress. Petersen: Yes. So, in the example you use with the pollution, Congress has something fairly specific in mind—a specific type of pollution—but the agency might have to clarify and to say what counts as pollution and how much they’re measuring it and maybe they might establish a quota system, they might have specific rules for specific firms. And in the other example you gave, which is just protecting consumers from unnecessary risk, in that case they can basically write rules as if they were their own legislator, they’re essentially doing what Congress is ostensibly meant to do. Is that correct? Jones: I’m not sure I would go that far. So, there are various theories of the purpose of the regulatory apparatus in the bureaucracy. Some people—I cite them in the paper—Baumgartner and Jones and Workman have one that is called ‘The Politics of Information’ and I forget what the other is called, it was written in 2015. And their theory instead is that Congress gives the agencies discretion because Congress doesn’t know the problems it needs to solve and so the agency is kind of like the specialists that you subcontracted to figure out what Congress wants them to solve without actually knowing, say the relevant information to determine that. That’s one theory. You’ve got other people like Philip Hamburger notably, who has written a whole book on how administrative law, which is another word for regulation, is unlawful and so he goes through sort of the common-law tradition and cites numerous pieces of evidence to say, exactly in the way that you put it, that it’s a deep legislative function and only Congress should be performing that. And so, whether that’s true I think depends on a number of different assumptions that aren’t always discussed directly in the literature. That would be my interpretation if that makes sense. Petersen: Right. And of course, we’re approaching this from an economic standpoint so there are important public choice issues involved with this. The same rule whether it’s written by a legislator or a bureaucracy—a regulatory agency— it’s the same rule and so in principle, there should be no difference. But the important thing is that the agency and the Congress may have different incentives and may write different rules. That’s what I interpret as an important underlying theme in your paper. Jones: That’s most certainly true. So, that’s actually one of the things that frustrate me greatly about reading a lot of these other, I think, great researchers who don’t in my opinion sufficiently consider the role of incentives. To couch it in Baumgartner’s or in Jones’ and Workman’s terms, okay, let’s assume that the purpose of the bureaucracy is to create the information that’s necessary to solve the national problems, whatever these supposed national problems are. Why would you assume that bureaucrats would supply the right amount of information in the right ways consistently throughout time? And it’s not clear to me that those incentive systems are ever worked out; or if you do work them out, I don’t think it actually shows that bureaucrats are beholden directly to Congress. So the big terminal literature, which comes from McNollgast, which is McCubbins, Noll, and Weingast, in the 80s is called Congressional dominance. They basically say that because Congress writes the rules they structure all the incentives and have all the tools at their disposal to monitor and police agencies. And I’m just deeply skeptical that that works as well as they describe.
Cardiac Output, Stroke volume, EDV, ESV, Ejection Fraction
Cardiac Physiology Basics. This video and other related images/videos (in HD) are available for instant download licensing here: https://www.alilamedicalmedia.com/-/galleries/images-videos-by-medical-specialties/cardiology-and-vascular-diseases ©Alila Medical Media. All rights reserved. Voice by: Sue Stern. Support us on Patreon and get FREE downloads and other great rewards: patreon.com/AlilaMedicalMedia CARDIAC OUTPUT is the amount of blood pumped by each ventricle in one minute. It is the product of STROKE VOLUME – the amount of blood pumped in one heartbeat, and HEART RATE – the number of beats in one minute. An INcrease in either stroke volume or heart rate results in INcreased cardiac output, and vice versa. For example, during physical exercises, the heart beats faster to put out more blood in response to higher demand of the body. It is noteworthy that the ventricles do NOT eject ALL the blood they contain in one beat. In a typical example, a ventricle is filled with about 100ml of blood at the end of its load, but only 60ml is ejected during contraction. This corresponds to an EJECTION fraction of 60%. The 100ml is the end-DIASTOLIC volume, or EDV. The 40ml that remains in the ventricle after contraction is the end-SYSTOLIC volume, or ESV. The stroke volume equals EDV minus ESV, and is dependent on 3 factors: contractility, preload, and afterload. Contractility refers to the force of the contraction of the heart muscle. The more forceful the contraction, the more blood it ejects. PRELOAD is RELATED to the end-diastolic volume. Preload, by definition, is the degree of STRETCH of cardiac myocytes at the end of ventricular filling, but since this parameter is not readily measurable in patients, EDV is used instead. This is because the stretch level of the wall of a ventricle INcreases as it’s filled with more and more blood; just like a balloon - the more air it contains, the more stretched it is. According to the Frank-Starling mechanism, the greater the stretch, the greater the force of contraction. In the balloon analogy, the more inflated the balloon, the more forceful it releases air when deflated. AFTERLOAD, on the other hand, is the RESISTANCE that the ventricle must overcome to eject blood. Afterload includes 2 major components: - Vascular pressure: The pressure in the left ventricle must be GREATER than the systemic pressure for the aortic valve to open. Similarly, the pressure in the right ventricle must exceed pulmonary pressure to open the pulmonary valve. In hypertension for example, higher vascular pressures make it more difficult for the valves to open, resulting in a REDUCED amount of ejected blood. - Damage to the valves, such as stenosis, also presents higher resistance and leads to lower blood output. All images/videos by Alila Medical Media are for information purposes ONLY and are NOT intended to replace professional medical advice, diagnosis or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition.
Views: 165795 Alila Medical Media
Challenges in the regulation of high cost treatments - An overview from Latin America
Ms. Lara Pereira and Ms. Daniela Sturzenegger - ANVISA Patients deserve access to the most effective and safe treatments. At the same time, pharmaceutical companies face high costs in drug development, manufacturing and marketing and therefore many are focusing on novel treatments that can provide high-profit margins. In countries where most of the population depends on Public Healthcare Systems, e.g. “SUS” in Brazil, how should ANVISA address the increasing portfolio of high-cost treatments in the face of the country’s limited government budget?
Views: 350 Stanford Video
Labor Markets and Minimum Wage: Crash Course Economics #28
How much should you get paid for your job? Well, that depends on a lot of factors. Your skill set, the demand for the skills you have, and what other people are getting paid around you all factor in. In a lot of ways, labor markets work on supply and demand, just like many of the markets we talk about in Crash Course Econ. But, again, there aren't a lot of pure, true markets in the world. There are all kinds of oddities and regulations that change the way labor markets work. One common (and kind of controversial one) is the minimum wage. The minimum wage has potential upsides and downsides, and we'll take a look at the various arguments for an against it. Crash Course is on Patreon! You can support us directly by signing up at http://www.patreon.com/crashcourse Thanks to the following Patrons for their generous monthly contributions that help keep Crash Course free for everyone forever: Mark, Eric Kitchen, Jessica Wode, Jeffrey Thompson, Steve Marshall, Moritz Schmidt, Robert Kunz, Tim Curwick, Jason A Saslow, SR Foxley, Elliot Beter, Jacob Ash, Christian, Jan Schmid, Jirat, Christy Huddleston, Daniel Baulig, Chris Peters, Anna-Ester Volozh, Ian Dundore, Caleb Weeks -- Want to find Crash Course elsewhere on the internet? Facebook - http://www.facebook.com/YouTubeCrashCourse Twitter - http://www.twitter.com/TheCrashCourse Tumblr - http://thecrashcourse.tumblr.com Support Crash Course on Patreon: http://patreon.com/crashcourse CC Kids: http://www.youtube.com/crashcoursekids
Views: 466614 CrashCourse
How to Get Your Weight Gain Hormones Under Control
Subscribe to Bright Side : https://goo.gl/rQTJZz For copyright matters please contact us at: [email protected] ---------------------------------------------------------------------------------------- It’s hard to imagine that our weight depends not only on the number of calories we consume but also on some invisible chemicals inside us. In fact, hormones influence our metabolic processes and command our body to store fat or to stop gaining it. We at Bright Side want our readers to be more knowledgeable when it comes to our bodies, especially if this knowledge helps us to become healthier and more beautiful. There are numerous factors that can influence body weight. Among them are our physical activity, genetics, eating habits, and stresses. However, the most important role in this process still belongs to the hormones which are responsible for the regulation of metabolism. These chemicals are the ones that tell your body to store or burn fat. ---------------------------------------------------------------------------------------- Our Social Media: Facebook: https://www.facebook.com/brightside/ Instagram: https://www.instagram.com/brightgram/ 5-Minute Crafts Youtube: https://www.goo.gl/8JVmuC  ---------------------------------------------------------------------------------------- For more videos and articles visit: http://www.brightside.me/
Views: 754140 BRIGHT SIDE
Energy. EG 1 - New business models and energy regulation
The evolution of the energy sector over the forthcoming decade depends significantly on legislation. National and international regulations and international agreements could either facilitate or suppress certain technological developments and the behind-the-scenes businesses that make them possible. Speaker: · Ron Pernick - Founder and managing director - Clean Edge Inc - Portland - USA · Alistair Buchanan - Former CEO - Office of Gas and Electricity Markets OFGEM - London - UK · Gil Soto Tolosa - European Business Development Manager, Lighting Solutions Centre (LSC) - Professional Lighting Solutions Europe - Eindhoven - The Netherlands Moderator: Michael Kavanagh - Energy and Utilities Reporter - Financial Times - London - UK Date: 19/11/2013 Time: 12:30:00
IPU Certificate of Continuing Regulatory Education (CCRE)
Certificate of Continuing Regulatory Education (CCRE) Are you a lifelong learner in the challenging field of public utility regulation? Effective regulation depends on informed regulators. Your commitment to professional development will now earn you a Certificate of Continuing Regulatory Education (CCRE) from the Institute of Public Utilities at Michigan State University. The CCRE is endorsed by the National Association of Regulatory Utility Commissioners (NARUC) and is available exclusively and free of charge to public-sector employees and personnel of nonprofit organizations. For more information: http://ipu.msu.edu/CCRE/index.php
Views: 166 IPUMSU
Procedure Turn - When Do You Have to Do It??
https://www.GoldMethod.com for Gold Seal Instrument Test Prep Image that you're on a long inbound leg on the ILS. There's a procedure turn! Do you have to fly it? The answer is "it depends". Watch for the details.
TBS Factoring Service: DOT Compliance: 10 Steps You Need To Know
Compliance violations can ground you as sure as engine trouble. A motor carrier’s survival depends on maintaining a high-level of compliance. Call TBS today 800-207-7661 or visit our website http://www.truckersbookkeepingservice.com/
Views: 119958 TBS Companies
How to Turbocharge the American Economy
Roughly half of the United States’ workforce depends on small businesses thriving. But high taxes and intrusive government regulations hurt these businesses and their workers. How would tax cuts for these small businesses benefit the U.S. economy and help just about everyone? Find out in this short video. Donate today to PragerU! http://l.prageru.com/2ylo1Yt Joining PragerU is free! Sign up now to get all our videos as soon as they're released. http://prageru.com/signup This video is part of a collaborative business and economics project with Job Creators Network. To learn more about JCN, visit https://www.jobcreatorsnetwork.com. Download Pragerpedia on your iPhone or Android! Thousands of sources and facts at your fingertips. iPhone: http://l.prageru.com/2dlsnbG Android: http://l.prageru.com/2dlsS5e Join Prager United to get new swag every quarter, exclusive early access to our videos, and an annual TownHall phone call with Dennis Prager! http://l.prageru.com/2c9n6ys Join PragerU's text list to have these videos, free merchandise giveaways and breaking announcements sent directly to your phone! https://optin.mobiniti.com/prageru Do you shop on Amazon? Click https://smile.amazon.com and a percentage of every Amazon purchase will be donated to PragerU. Same great products. Same low price. Shopping made meaningful. VISIT PragerU! https://www.prageru.com FOLLOW us! Facebook: https://www.facebook.com/prageru Twitter: https://twitter.com/prageru Instagram: https://instagram.com/prageru/ PragerU is on Snapchat! JOIN PragerFORCE! For Students: http://l.prageru.com/29SgPaX JOIN our Educators Network! http://l.prageru.com/2c8vsff Script: Small businesses are the engine of the American economy. There are 29 million of them and they provide employment for roughly half the U.S. workforce. Through innovative products, dedicated employees, and strong community roots, these entrepreneurs are responible for two thirds of all job Creation. That’s a lot of jobs. But high taxes and intrusive government regulation can eat away at budgets and hurt their ability to raise wages and hire new people. In fact, small business owners say that high fedreal tax rates are their number one concern. Most small businesses – 95 percent of them, in fact – are taxed through the owner, which mean these businesses are subject to federal tax rates that can reach 40 percent. Small businesses structured like this are commonly referred to as pass throughs. Imagine 40 cents of every new dollar earned going to the government. In any other circumstance, theft on this level would not be tolerated. Why is it for small businesses? Significant tax cuts for these small enterprises would turbo charge the U.S. economy. According to a recent poll of small business owners, a majority of respondents would use the financial savings from tax cuts to invest back into their businesses. This means hiring more people, raising wages, and expanding operations. By energizing America’s entrepreneurial through small business tax cuts, America’s middle class can experience greater job security, higher wages, and a more vibrant main street.
Views: 419760 PragerU
Attachment Theory and Emotion Regulation
Halifax Psychologist, Brad Peters, talks about attachment theory and emotion regulation, as it relates to emotional intelligence, connection in relationships, and psychological resilience. Attachment is a term that describes an emotional bond – initially in childhood, with the parent or caregiver, but then later in life as well, with close friendships and romantic partners. When an infant is in distress, it will be almost instinctual for most adults or caregivers to provide comfort. We do this through our physical touch, soothing tone of voice, and eye contact. Research suggests that these kinds of behaviors promote the release of dopamine (neurotransmitter involved in pleasure/elation) and endogenous opiates (the body’s natural painkillers). It is also useful to remember the axiom: “neurons that fire together, wire together.” The parent finds the infant in a state of nervous system distress or chaos, and then uses their body, to move the body of the infant, into a state of calm or equanimity. When this happens with repetition and consistency, over time, the nervous system of that infant will ‘learn’ (like muscle memory for neurons) to more readily shift from a state of distress to a state of relative calm – this marks the very beginnings of what we call Emotion Regulation: the ability to tolerate, and ultimately regulate, high levels of emotional distress, without being flooded by feeling, or having to engage in various forms of psychological repression. Fast-forwarding into childhood, we can imagine a child feeling sad. The tears are streaming down their cheeks, facial expressions suggest that they are in emotional pain, and their body posture is slumped over. In a perfect world (which only happens about 50% of the time), a parent will meet the child at eye level (dropping to one knee), will comfort them physically, and will offer that familiar tone of voice that the child intuitively recalls from childhood – and for all the reasons described, it feels good. But with language, now parents are ideally ASKING their child what they might be feeling, and the circumstances that led to them. When the parent guesses correctly, the child feels like their parents understand, and if the parent is moved by their hurting child, the child feels themselves being felt by another. When this happens, it makes these painful emotions, which are almost unbearable in isolation, now bearable. If we have these kinds of experiences in childhood, we tend to grow into adults with high emotional intelligence, who are able to experience and express their feelings, and who feel comfortable relying on others for psychological support. Those who receive less than that, because parents were perhaps not very good with feelings, took a problem-solving approach to addressing emotion, or used distraction or guilt to suppress them, tend to develop into adults with avoidant or anxious-ambivalent styles of attachment. The important point to keep in mind is that while attachment styles are programmed early and unconsciously, once they are identified and made conscious, they can be changed. It is hard work, for sure, but this ‘earned secure attachment,’ will mean an end to maladaptive emotional patterns, that prevent us from dealing effectively with feelings, and that keep us stuck in unhealthy relationship dynamics. If you found this video helpful, please take a moment to subscribe to our channel. CPS YouTube Channel: https://www.youtube.com/user/HalifaxPsychologists CPS Mental Health Blog: http://www.cornerstoneclinic.ca/blog/ CPS Facebook: https://www.facebook.com/CornerstonePsychologicalServices Brad Peters' Website: http://www.bpeters.ca/ Our video content is intended for general public use and knowledge. We have the best of intentions in doing so, and derive our information from material thought to be reliable, valid, and supported by relevant research at the time of production. However, it is ultimately the responsibility of the viewer to assess and evaluate this information, and the statements provided, in light of their own situation or individual circumstances. We offer information that is both general and broad; it is not intended to, nor should, replace a qualified mental health practitioner who is able to make judgments and decisions based on first-hand knowledge of an individual and their situation.
Elizabeth Warren - The State of the Insurance Industry and Insurance Regulation
April 28, 2015. UNITED STATES SENATE COMMITTEE ON BANKING, HOUSING, AND URBAN AFFAIRS met in OPEN SESSION to conduct a hearing entitled, “The State of the Insurance Industry and Insurance Regulation.” The witnesses were: The Honorable S. Roy Woodall, Jr., Independent Member with Insurance Expertise, Financial Stability Oversight Council; Mr. Mark Van Der Weide, Deputy Director, Division of Banking Supervision and Regulation, Board of Governors of the Federal Reserve System; Mr. Michael McRaith, Director, Federal Insurance Office, U. S. Department of the Treasury; and Mr. Kevin McCarty, Commissioner, Florida Insurance Department, on behalf of the National Association of Insurance Commissioners.
Views: 434 Marie Marr
Pharmacology - ANTIDEPRESSANTS - SSRIs, SNRIs, TCAs, MAOIs, Lithium ( MADE EASY)
💪⚡ Try Online Counseling: http://tryonlinetherapy.com/speedpharmacology If you are struggling with depression or any other mental illness consider online counseling with a licensed professional at BetterHelp. It’s far cheaper and more convenient than in-person counseling. Believe me, you are worth it. By using my referral link, you support this channel. Support us on Patreon: https://www.patreon.com/speedpharmacology Follow us on Facebook: https://www.facebook.com/SpeedPharmacology/ Get Speed Pharmacology Merch Here: https://teespring.com/stores/speed-pharmacology **************************************************************************************************** Topics covered in this video include: monoamine hypothesis of depression, bipolar disorder, serotonin, norepinephrine, dopamine, receptors, mechanism of action of antidepressants; selective serotonin reuptake inhibitors, serotonin norepinephrine reuptake inhibitors ,tricyclic antidepressants, monoamine oxidase inhibitors, atypical antidepressants, and lithium. Antidepressants mentioned include: Citalopram, Escitalopram, Fluoxetine, Fluvoxamine, Paroxetine, Sertraline, Venlafaxine, Desvenlafaxine, Duloxetine, Levomilnacipran, Amitriptyline, Amoxapine, Clomipramine, Desipramine, Doxepin, Imipramine, Maprotiline, Nortriptyline, Protriptyline, Isocarboxazid, Phenelzine, Tranylcypromine, Selegiline, Bupropion, Mirtazapine, Trazodone, Nefazodone, Vilazodone, and Vortioxetine.
Views: 341462 Speed Pharmacology
The Earth's Energy Balance
Earth's energy balance will enable you to understand radiative equilibrium. You will also be able to recognize that the temperature of earth depends on the amount of solar energy that it absorbs. Read more about Earth's Energy Budget here http://earthobservatory.nasa.gov/Features/EnergyBalance/?src=youtube
Views: 131487 NASAEarthObservatory
The real reason American health care is so expensive
Hint: single-payer won’t fix America’s health care spending. Subscribe to our channel! http://goo.gl/0bsAjO Americans don't drive up the price by consuming more health care. They don't visit the doctor more than other developed countries: http://international.commonwealthfund.org/stats/annual_physician_visits/ But the price we pay for that visit - for a procedure - it costs way more: http://static1.squarespace.com/static/518a3cfee4b0a77d03a62c98/t/57d3ca9529687f1a257e9e26/1473497751062/2015+Comparative+Price+Report+09.09.16.pdf The price you pay for the same procedure, at the same hospital, may vary enormously depending on what kind of health insurance you have in the US. That's because of bargaining power. Government programs, like Medicare and Medicaid, can ask for a lower price from health service providers because they have the numbers: the hospital has to comply or else risk losing the business of millions of Americans. There are dozens of private health insurance providers in the United States and they each need to bargain for prices with hospitals and doctors. The numbers of people private insurances represent are much less than the government programs. That means a higher price when you go to the doctor or fill a prescription. Uninsured individuals have the least bargaining power. Without any insurance, you will pay the highest price. For more health care policy content, check out The Impact, a podcast about the human consequences of policy-making. https://itunes.apple.com/us/podcast/the-impact/id1294325824?mt=2 Vox.com is a news website that helps you cut through the noise and understand what's really driving the events in the headlines. Check out http://www.vox.com to get up to speed on everything from Kurdistan to the Kim Kardashian app. Check out our full video catalog: http://goo.gl/IZONyE Follow Vox on Twitter: http://goo.gl/XFrZ5H Or on Facebook: http://goo.gl/U2g06o
Views: 2604717 Vox
Increased Intracranial Pressure Nursing Pathophysiology NCLEX Symptoms (Cerebral Perfusion Pressure)
Increased intracranial pressure (ICP) nursing, pathophysiology, NCLEX, treatment, and symptoms NCLEX review. Increased intracranial pressure occurs when the inside of the skull experiences increased pressure. This is a medical emergency! How is ICP created? Intracranial pressure is the pressure created by the cerebrospinal fluid and brain tissue/blood within the skull. It can be measured in the lateral ventricles with an external ventricular drain (ventriculostomy). What is a normal intracranial pressure (ICP)? 5-15 mmHg (greater than 20 mmHg…needs treatment) Pathophysiology of increased intracranial pressure: The human skull is very hard and is limited on how much it can expand when something inside the skull experiences a change that leads to increased pressure exerted within the skull. Inside the skull are three structures that can alter intracranial pressure: brain, cerebrospinal fluid (CSF), and blood. The Monro-Kellie hypothesis deals with how ICP is affected by CSF, brain's blood, and tissue that works to maintain cerebral perfusion pressure (CPP). In a nutshell, this hypothesis says that when the volume of one of these structures increases than the others will have to decrease their volume to compensate for the increased intracranial pressure. Intracranial pressure fluctuates and this depends on many factors like: the person’s body temperature, oxygenation status, especially CO2 and O2 levels, body position, arterial and venous pressure, anything that increases intra-abdominal or thoracic pressure (vomiting, bearing down). Cerebral perfusion pressure is important when dealing with intracranial pressure. A normal CPP is 60-100 mmHg. When CPP (pressure that pushes the blood to the brain) falls too low the brain is not perfused and brains tissue dies. How is CPP calculated? CPP= MAP - ICP (see video on how to calculate cerebral perfusion pressure) Symptoms of increased intracranial pressure: mental status changes (EARLIEST), cushing's triad, vomiting, headache, decorticate or decerebrate posturing, optic and oculomotor nerve damage, abnormal doll's eye, seizures etc. Nursing care for increased ICP includes monitoring and preventing further increases in intracranial pressure, administering drugs such as Mannitol, anticonvulsants, corticosteroids etc. See video for a mnemonic on the nursing interventions for increased ICP. Increased Intracranial Pressure NCLEX Questions: http://www.registerednursern.com/increased-intracranial-pressure-icp-nclex-questions/ Notes: http://www.registerednursern.com/increased-intracranial-pressure-icp-nclex-review/ More Neuro Videos: https://www.youtube.com/playlist?list=PLQrdx7rRsKfVPDxuXWcpmg42nNXdjA9FD Facebook: https://www.facebook.com/RegisteredNurseRNs Instagram: https://www.instagram.com/registerednursern_com/ Subscribe: http://www.youtube.com/subscription_center?add_user=registerednursern Nursing School Supplies: http://www.registerednursern.com/the-ultimate-list-of-nursing-medical-supplies-and-items-a-new-nurse-student-nurse-needs-to-buy/ Popular Playlists: NCLEX Reviews: https://www.youtube.com/playlist?list=PLQrdx7rRsKfWtwCDmLHyX2UeHofCIcgo0 Fluid & Electrolytes: https://www.youtube.com/playlist?list=PLQrdx7rRsKfWJSZ9pL8L3Q1dzdlxUzeKv Nursing Skills: https://www.youtube.com/playlist?list=PLQrdx7rRsKfUhd_qQYEbp0Eab3uUKhgKb Nursing School Study Tips: https://www.youtube.com/playlist?list=PLQrdx7rRsKfWBO40qeDmmaMwMHJEWc9Ms Nursing School Tips & Questions" https://www.youtube.com/playlist?list=PLQrdx7rRsKfVQok-t1X5ZMGgQr3IMBY9M Teaching Tutorials: https://www.youtube.com/playlist?list=PLQrdx7rRsKfUkW_DpJekN_Y0lFkVNFyVF Types of Nursing Specialties: https://www.youtube.com/playlist?list=PLQrdx7rRsKfW8dRD72gUFa5W7XdfoxArp Healthcare Salary Information: https://www.youtube.com/playlist?list=PLQrdx7rRsKfVN0vmEP59Tx2bIaB_3Qhdh New Nurse Tips: https://www.youtube.com/playlist?list=PLQrdx7rRsKfVTqH6LIoAD2zROuzX9GXZy Nursing Career Help: https://www.youtube.com/playlist?list=PLQrdx7rRsKfVXjptWyvj2sx1k1587B_pj EKG Teaching Tutorials: https://www.youtube.com/playlist?list=PLQrdx7rRsKfU-A9UTclI0tOYrNJ1N5SNt Dosage & Calculations for Nurses: https://www.youtube.com/playlist?list=PLQrdx7rRsKfUYdl0TZQ0Tc2-hLlXlHNXq Diabetes Health Managment: https://www.youtube.com/playlist?list=PLQrdx7rRsKfXtEx17D7zC1efmWIX-iIs9
Views: 113604 RegisteredNurseRN
The Art and Science of Capital Structure
Optimal capital structure is a moving target. It's unique to each company and depends on capital market conditions, the economy, management capabilities, industry trends and--most importantly--the regulatory environment and social trends. Getting these wrong can have significant consequences. Overleveraging can leave a company hamstrung, just as avoiding debt at the wrong times can lead to missed opportunities for growth and job creation. For some companies, the constant focus on short-term financing leaves less time for long-term planning. Finding the right capital structure is both an art and a science, and the best practitioners understand their environment and draw from a broad range of financial tools. This panel will discuss why capital structure matters now more than ever. How are risk levels affected by current government regulation and social trends? When is it time to build liquidity? How can companies anticipate interest-rate and market cycles to avoid the wrong structure?
Views: 10426 Milken Institute
Help Save Our Wilderness
Wilderness is a precious and fragile resource. A few simple rules of self-conduct will permit you to enjoy an exceptional wilderness experience. Enduring the quality of wilderness depends on you. Help protect the wilderness by following the wilderness regulations and incorporating wilderness ethics into your backcountry activities. Camping within 200’ of designated trail, a body of water, or an occupied campsite. Stay limit is 14 consecutive days. No groups larger than 14. Pack out your trash. Dispose of human waste properly by digging a cat hole 6-8” deep and bury it. No more than 15 head of stock. Must have certified weed free hay or pellets. Tethering or restraining saddle or pack stock for longer than one hour within 200’ of water, or if it is causing resource damage. No Shortcutting trails or switchbacks. Do not build any type of structure or improvements. IE: hitch rails, furniture, shelters, and rafts. In the wilderness, you will have the opportunity to experience challenge, self-reliance, and the reward of discovery; but you are also responsible for your own safety. In an area that is unfamiliar or new, there are few posted signs, so you must know how to read a map and use a compass. You must be prepared for accidents and dramatic changes in weather. The 1964 Congress enacted the Wilderness Act, which established the National Wilderness Preservation System... to secure for the American people of present and future generations the benefits of an enduring resource of wilderness. Wilderness Areas are closed to all types of motor vehicles, mechanical transport, hang gliders, and bicycles. Activities specifically prohibited in the Wilderness Act are: commercial enterprises; roads and structures; the landing of aircraft; the use of motorized equipment; and motor or mechanical transport. Before visiting a Wilderness Area, check with the appropriate Forest Service office for regulations. Please follow all visitor rules and practice good safety when visiting the National Forests. Filmed and edited by Charity Parks
Views: 657 Forest Service
How the Eye Works Animation - How Do We See Video - Nearsighted & Farsighted Human Eye Anatomy
The eye is the organ of sight and is shaped as a slightly irregular hollow sphere. Various structures in the eye enable it to translate light into recognizable images. Among these are the cornea, the lens, and the retina. Light first passes through the cornea, a clear dome-like structure covering the iris, or colored part, of the eye. The cornea bends, or refracts, the light onto the lens. The light is then refracted a second time while passing through the lens, finally focusing on the retina. The retina is the light sensitive part of the eye. Impulses travel down the optic nerve to the occipital lobe of the brain, which then interprets the image in the correct perspective. The shape of the eye is very important in keeping the things we see in focus. If the shape of the eye changes, it affects a person’s vision. Normally, light is precisely focused onto the retina at a location called the focal point. A nearsighted eye is longer from front to back than a normal eye causing light to be focused in front of the retina instead of directly onto it. This makes it difficult to see objects that are far away. Glasses with concave lenses are used to correct nearsightedness. The concave lens focuses light back onto the focal point of the retina. Farsightedness occurs when the length of the eye is too short. Light is focused at a point behind the retina, making it difficult to see objects that are up close. A convex lens is used to correct farsightedness because it directs the focal point back onto the retina. How Your Eyes Work When light rays reflect off an object and enter the eyes through the cornea (the transparent outer covering of the eye), you can then see that object. Rods and Cones in the retina The cornea bends, or refracts, the rays that pass through the round hole of the pupil. The iris (the colored portion of the eye that surrounds the pupil) opens and closes, making the pupil bigger or smaller. This regulates the amount of light passing through. The light rays then pass through the lens, which changes shape so it can further bend the rays and focus them on the retina. The retina, which sits at the back of the eye, is a thin layer of tissue that contains millions of tiny light-sensing nerve cells. These nerve cells are called rods and cones because of their distinct shapes. Cones are concentrated in the center of the retina, in an area called the macula. When there is bright light, cones provide clear, sharp central vision and detect colors and fine details. Rods are located outside the macula and extend all the way to the outer edge of the retina. They provide peripheral or side vision. Rods also allow the eyes to detect motion and help us see in dim light and at night. These cells in the retina convert the light into electrical impulses. The optic nerve sends these impulses to the brain, which produces an image. The human eye is an organ that reacts to light and has several purposes. As a sense organ, the mammalian eye allows vision. Rod and cone cells in the retina allow conscious light perception and vision including color differentiation and the perception of depth. The human eye can distinguish about 10 million colors and is possibly capable of detecting a single photon. Similar to the eyes of other mammals, the human eye's non-image-forming photosensitive ganglion cells in the retina receive light signals which affect adjustment of the size of the pupil, regulation and suppression of the hormone melatonin and entrainment of the body clock. Visual perception is the ability to interpret the surrounding environment by processing information that is contained in visible light. The resulting perception is also known as eyesight, sight, or vision (adjectival form: visual, optical, or ocular). The various physiological components involved in vision are referred to collectively as the visual system, and are the focus of much research in Linguistics, psychology, cognitive science, neuroscience, and molecular biology, collectively referred to as vision science. Light entering the eye is refracted as it passes through the cornea. It then passes through the pupil (controlled by the iris) and is further refracted by the lens. The cornea and lens act together as a compound lens to project an inverted image onto the retina. The retina consists of a large number of photoreceptor cells which contain particular protein molecules called opsins. In humans, two types of opsins are involved in conscious vision: rod opsins and cone opsins. (A third type, melanopsin in some of the retinal ganglion cells (RGC), part of the body clock mechanism, is probably not involved in conscious vision, as these RGC do not project to the lateral geniculate nucleus but to the pretectal olivary nucleus.) An opsin absorbs a photon (a particle of light) and transmits a signal to the cell through a signal transduction pathway, resulting in hyper-polarization of the photoreceptor. Rods and cones differ in function.
Views: 460453 AniMed
Road rules: yellow lights
Brush up on your road rule knowledge by viewing the top ten misunderstood road rules animations. The animations outline some of the rules the NSW community have said they need more clarification on, like mobile phone laws, roundabout rules and how and why we enforce in school zones. Road safety largely depends on road users being able to understand and follow the road rules, so share the animation links with your friends and colleagues and refresh your memory! For more information on road rules download the Top 10 misunderstood road rules in NSW guide (http://roadsafety.transport.nsw.gov.au/downloads/campaigns/top10_misunderstood.html) or visit http://roadsafety.transport.nsw.gov.au or http://www.rms.nsw.gov.au/. Like Us on Facebook: http://www.facebook.com/transportfornsw Follow Us on Twitter: http://www.twitter.com/transportfornsw See Us on Instagram: http://www.instagram.com/transportfornsw
Views: 164159 Transport For NSW
Dear Bianca: Use your heart to build your baby's brain | Vonda Jump | TEDxUSU
Recent brain research is clear: babies’ brains develop through their interactions with their primary caregivers, and the types of interactions they have impact their brains differentially. Babies depend on their primary caregivers for physiological self-regulation and brain organization in the early months. What babies need is a consistent, sensitive, and appropriately responsive caregiver for optimal development. In this regard, the baby’s brain mirrors the parent’s heart. Vonda Jump Norman is a researcher in the Research and Evaluation Division of the Center for Persons with Disabilities in the College of Education, with an emphasis on systems of care affecting infants in orphanages, parent-child relationships during the first years of a child’s life, and an interest in the intersection of physical and mental health. She is the Principal Investigator of several projects, including a Department of Defense project to investigate the effects of infant massage on father-infant relationships on military installations with high rates of deployment to Iraq and/or Afghanistan. Vonda has conducted training and/or research in orphanages in Ecuador, Haiti, India, and Russia. “What inspires me in my field is visiting an orphanage where caregivers work so hard and have so little education and means, and they are there every day taking care of babies,” Vonda said. This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at http://ted.com/tedx
Views: 3659 TEDx Talks
2018 Mazda CX-3
The 2018 Mazda CX-3 responds to customer feedback with design and technology advances in several key areas. In a design which raises the standard of radical styling and eye-catching elegance, Mazda’s compact SUV combines a flexible, driver-oriented interior with superb engineering and painstaking attention to detail, making it a more compelling proposition than ever before. A new SKYACTIV-D 1.8 litre diesel engine (fuel consumption: 4.4-5.2 l/100 km; CO2: 114-137 g/km)1 makes its first appearance in the 2018 Mazda CX-3, offering drivers both enhanced responsiveness and improved emissions performance. Two SKYACTIV-G 2.0 litre gasoline engines (fuel consumption: 6.1-7.0 l/100 km; CO2: 140-160 g/km)1 now feature the innovations first adopted in the current Mazda CX-5, including edge-cut piston heads and high-dispersion injectors. These technical developments ensure ample torque throughout the entire rev range and contribute to better real-world fuel efficiency. All three engines meet the stringent new Euro 6d-TEMP emission standards, including the real-drive emission test (RDE). Exterior design enhancements include an updated front grille, the adoption of LED rear combination lamps, new aluminium alloy wheels, and -making its premiere in the 2018 CX-3 line-up- Mazda’s unique colour, Soul Red Crystal. On board, a higher quality interior is free of non-essential elements in keeping with the Japanese aesthetic of eliminating excess to create beauty. A redesigned centre console with an electric parking brake and a multi-box centre armrest enhance comfort and reduce fatigue. A new special edition model will be available featuring deep red Nappa leather upholstery and 18” bright silver alloy wheels2 The adoption of the latest developments in Mazda’s next-generation SKYACTIV-Vehicle Architecture has significantly evolved the CX-3’s driving performance from the human-centred perspective of vehicle-total optimisation. Further suspension system tuning, newly developed tires and the use of higher-damping urethane in the front seat construction provide a quieter and more comfortable ride, and an even more engaging driving experience. Safety has also been significantly improved in the 2018 Mazda CX-3. It adopts an updated version of Advanced Smart City Brake Support (Advanced SCBS), which has an enhanced ability to detect pedestrians at night. This, and other safety features such as Mazda Radar Cruise Control (MRCC) with Stop & Go-function3 and an auto-dimming rear-view mirror, ensures a higher level of safety under all driving conditions. 1 Vehicles are homologated in accordance with the new type approval procedure WLTP (Regulation (EU) 1151 / 2017; Regulation (EU) 2007/715). To provide comparability the referred values are NEDC – values determined in line with Implementation Regulation (EU) 1153 / 2017 2 Availability depends on market 3 Stop & Go-function for vehicles with SKYACTIV-Drive only VIA: MAZDA
Views: 71 Dan Strauti
Enzi seeks to overturn health care regulation
U.S. Senator Mike Enzi, R-Wyo., Ranking Member of the Senate Health, Education, Labor and Pensions Committee (HELP Committee) today urged the Senate to move forward on the consideration of a Resolution of Disapproval that would overturn a new health care regulation that breaks the President's promise "If you like what you have you can keep it."
Views: 1493 Senator Enzi
गज़ब! सिर्फ 7 दिन में अपनी लम्बाई बढ़ाये और आकर्षक दिखें | How to Increase Height and Look Attractive
Height is one of the most important 'feature' that is present in your body. The characteristic of 'Good Height' actually boosts your self confidence. Yes, it is a fact that height effects one's personality. If your height is shorter than your friends, you may not feel good but the good news is that you can increase your height by various natural exercises and techniques. 90 percent of your Height depends upon your genes but there are many ways you can do wonders with the rest of the 10 percent that is in your hands. In this video, I explained you how to increase height. Good nutrition is also a very important part of this process. A good sleep is also a very important factor. Hormones secreted from the pituitary gland help control: growth, pressure, thyroid glands and metabolism , temperature regulation and pain relief. I explained you the role of Human Growth Hormone for height growth. Information References: https://en.wikipedia.org/wiki/Growth_hormone https://www.ncbi.nlm.nih.gov/pubmed/8614759 Social Pages: Like the Facebook Page! - https://www.facebook.com/facttechz/ Follow on Instagram - https://www.instagram.com/facttechz/ Follow On Twitter! - https://twitter.com/facttechz Follow on Google+ - https://plus.google.com/+FactTechz/ Computer Software I use: Adobe After Effects for Video Compositing Sony Vegas Pro for Video Effects, Mixing and Syncing Adobe Premier Pro for Final Video Editing Adobe Audition for Music and Sound Effect Adjustments
Views: 12114541 FactTechz
Dr. Allan N. Schore - Modern attachment theory; the enduring impact of early right-brain development
Dr. Schore is on the clinical faculty of the Department of Psychiatry and Biobehavioral Sciences, UCLA David Geffen School of Medicine, and at the UCLA Center for Culture, Brain, and Development. In this talk at our 2012 Research Symposium, he talks about the importance in a newborn's life of a secure, primary attachment to a psychobiologically-attuned empathic caregiver. The empathic caregiver can soothe and calm as well as as enhance joy, interest and excitement. This shapes the child’s ability to communicate emotions. This plays an important role in infant brain development, and ultimately, the caregiver influences the critical wiring of infant brain circuits. The self-organization of an infant's developing brain occurs in the context of a relationship with another self, another brain. There is now consensus, he says, "that current advances in our understanding of how social forces shape early brain development is 'one of the most important discoveries in all of science that have major implications for our field.'" An Empathy Enterprise TM Initiative © Roots of Empathy TM
Views: 24525 RootsofEmpathy
Is it worth to start a  Cryptocurrency Brokerage business?
Is it worth to start a Cryptocurrency Brokerage and what are the commissions? Yes and no – it depends in those factors that you will see at the video. Get more information here - https://www.gbo-intl.com/cryptocurrecy-regulation-licenses-bitcoin-ethereum/ ▼ See More Fintech and Financial videos ▼ ► See our playlists ▼ Payments - https://www.youtube.com/playlist?list=PLdWmG4gTw7E3P00mfgAowhrtNjx5rEySU How to start - https://www.youtube.com/playlist?list=PLdWmG4gTw7E08qMtX2aovcrLxCCPO4fWg Regulation - https://www.youtube.com/playlist?list=PLdWmG4gTw7E2D-GhDWb4SNavHzo0BdjD0 Cryptocurrency - https://www.youtube.com/playlist?list=PLdWmG4gTw7E0IqGGh25Tkdn_yptq1KfV7 Banking - https://www.youtube.com/playlist?list=PLdWmG4gTw7E3P00mfgAowhrtNjx5rEySU ► Previous Videos ▼ ► Subscribe To See More :) https://www.youtube.com/channel/UCPwGgfSjg7pRZvixG-tyFYA
Views: 6042 FintechZone
Garry Kasparov's Top 10 Rules For Success (@Kasparov63)
He's a Russian chess Grandmaster, former World Chess Champion, writer, and political activist. He's considered by many to be the greatest chess player of all time. He became the youngest ever undisputed World Chess Champion at age 22 by defeating then-champion Anatoly Karpov. He's Garry Kasparov and here are his Top 10 Rules for Success. * Join my BELIEVE newsletter: http://www.evancarmichael.com/newsletter/ 1. Recognize your own strengths and weaknesses He first began the serious study of chess after he came across a chess problem set up by his parents and proposed a solution. 2. Care Passionately At the age of 10, he began training at Mikhail Botvinnik's chess school under noted coach Vladimir Makogonov. 3. Make a difference He participated in the Sokolsky Memorial tournament. He had been invited as an exception but took first place and became a chess master. 4. Persevere He first qualified for the Soviet Chess Championship at age 15, the youngest ever player at that level. 5. Enter uncharted waters He rose quickly through the World Chess Federation rankings. 6. Be flexible In January 1984, Kasparov became the No. 1 ranked player in the world, with a FIDE rating of 2710. 7. Trust your gut From 1986 until his retirement in 2005, Kasparov was ranked world No. 1 for 225 out of 228 months. 8. Learn from your mistakes He also holds records for consecutive professional tournament victories (15) and Chess Oscars (11). 9. Seek new challenges He announced his retirement from professional chess on 10 March 2005, after which he devoted his time to politics and writing. 10. Success depends on you He formed the United Civil Front movement, and joined as a member of The Other Russia. Sources: https://youtu.be/NPT0vg_Jl8Q https://www.youtube.com/watch?v=kZqcT66Fkzw https://youtu.be/egAgvLgk848 https://youtu.be/eQgHXLZnvEE https://www.youtube.com/watch?v=B2KKfOGaR_w WHAT IS BTA? * Find out here: https://www.youtube.com/watch?v=BsY8bmTUVP8 ENGAGE * Subscribe to my channel: http://www.youtube.com/subscription_center?add_user=Modelingthemasters * Leave a comment, thumbs up the video (please!) * Suppport me: http://www.evancarmichael.com/support/ CONNECT * Twitter: https://twitter.com/evancarmichael * Facebook: https://www.facebook.com/EvanCarmichaelcom * Google+: https://plus.google.com/108469771690394737405/posts * Website: http://www.evancarmichael.com EVAN * About: http://www.evancarmichael.com/about/ * Guides: http://www.evancarmichael.com/zhuge/ * Coaching: http://www.evancarmichael.com/movement/ * Speaking: http://www.evancarmichael.com/speaking/ * Gear: http://evancarmichael.com/gear WEEKDAY SCHEDULE * #Entspresso - Weekdays at 7am EST : https://www.youtube.com/playlist?list=PLiZj-Ik9MmM0-kQSSs3Ua5wExlz1HwRRs * Lunch & Earn - Weekdays at 12pm EST: https://www.youtube.com/playlist?list=PLiZj-Ik9MmM1j5wXSEqRxhu_MK0g4TA4M * Top 10 Rules for Success - Weekdays at 8pm EST: https://www.youtube.com/playlist?list=PLiZj-Ik9MmM0VWRGYCfuUCdyhKfU733WX WEEKEND SCHEDULE * #Entvironment - Saturdays at 7am EST: https://www.youtube.com/playlist?list=PLiZj-Ik9MmM3ZvpIdZoneTe1KYCVcmfbF * #EvansBook - Saturdays at 8pm EST: https://www.youtube.com/playlist?list=PLiZj-Ik9MmM1tNSh0CjOsqIg1fw7bAPt4 * #BelieveLife - Sundays at 7am EST: https://www.youtube.com/playlist?list=PLiZj-Ik9MmM207_RQCOPAwZdKYXQ4cqjV * Life with Evan - Sundays at 8pm EST: https://www.youtube.com/playlist?list=PLiZj-Ik9MmM19tzfHH_VJOnghbfdRPZjS
Views: 210644 Evan Carmichael
Enterprise IPv6 Adoption Status? Depends Where by Yves Poppe at gogoNET LIVE! 3 IPv6 Conference
gogo6 IPv6 Video Series. Event, presentation and speaker details below: EVENT gogoNET LIVE! 3: Enterprise wide Migration. http://gogonetlive.com November 12 -- 14, 2012 at San Jose State University, California Agenda: http://gogonetlive.com/4105/gogonetlive3-agenda.asp PRESENTATION Enterprise IPv6 Adoption Status? Depends Where on Earth you Are Abstract: http://www.gogo6.com/profiles/blogs/gogonet-live-3-presentation-ipv6-in-the-enterprise-depends-where Slides: http://gogonetlive.com/pdf/3/yves_poppe.pdf SPEAKER Yves Poppe - Director of Business Development, IP Services, Tata Communications Bio/Profile: http://www.gogo6.com/profile/YvesPoppe Corresponding interview: http://www.gogo6.com/video/interview-with-yves-poppe-at-gogonet-live-3-ipv6-conference MORE Learn more about IPv6 on the gogoNET social network http://www.gogo6.com Get free IPv6 connectivity with Freenet6 http://www.gogo6.com/Freenet6 Subscribe to the gogo6 IPv6 Channel on YouTube http://www.youtube.com/subscription_center?add_user=gogo6videos Follow gogo6 on Twitter http://twitter.com/gogo6inc Like gogo6 on Facebook http://www.facebook.com/pages/IPv6-products-community-and-services-gogo6/161626696777
Views: 84 gogo6videos
"Taxation Is Theft" | Austrian Economics Metal
✔️Support the channel: https://www.patreon.com/finntronaut ✔️Back-up channel: https://www.youtube.com/finntronaut ✔️Back-up channel 2: https://www.youtube.com/channel/UCUi8Q1cWJa2yvUCIVJXs5aA ✔️Twitter: https://twitter.com/finntronaut ✔️Minds: https://minds.com/finntronaut ✔️Gab: https://gab.ai/finntronaut Lyrics: "Money has no inherent value It's only worth what people will give you (for it) Nothing has objective worth Different things by different people are differently preferred A rich person with all of his money Consumes just three meals per day Economy is not a zero-sum game Fortunes of one causes no poverty To end hunger, you need not money (You need food) To end poverty, you need not money (You need to produce) So listen to the words said by Karl Marx Capitalism is a crisis in ABUNDANCE You're a useful fool who claps his hands (When your masters hide money stolen from you) Behind one wall of separation (Taxation is theft and you know it's true) NPC: "Taxation is the price we pay to live in a civilized society." NPC: "This is extremely dangerous to our democracy." NPC: "Assimilate or be destroyed." When you print money, you have only degraded the value of singular units generated (It is called the marginal utility rate) Scarcity, demand are the bearers of value Prices lower as you increase the produce To maximize production you need to incentivize Taxation discourages enterprise 'Cause you don't get to keep your own labor's fruits And people work hardest for their own good Big business benefits from lack of competition Hence they lobby for more regulation The monopolies of which you're so afraid Love the barrier to a rival of theirs According to the subjective theory of value every dollar used by government instead of you cannot be used to the same degree of efficiency 'cause your values differentiate from those of the state Your labor only has value if someone agrees that it does. How much it is worth depends upon: 1: How much one is willing to pay for it 2: How low you're willing to work for 3: How rare your skill is 4: How many people want your work Government loves goals that can't be achieved 'Cause this way they can grow incessantly Their desire for equality is pure insanity 'Cause equality grows as markets get freed Everyone knows best what they themselves want And what people want is the demand Demand is what incentivizes production Economy works fine without your intervention" #LaissezFaire #Voluntaryism #AnarchoCapitalism
Views: 740 Finntronaut
Meet geneticist Sadhan Majumder, Ph.D.
Dr. Majumder completed his predoctoral schooling at Saha Institute of Nuclear Physics in India and received his Ph.D. from New York University. He subsequently completed his postdoctoral training at Sloan Kettering Cancer Center and at Roche Institute of Molecular Biology. He joined The University of Texas M. D. Anderson Cancer Center in 1995 as an Assistant Professor and was promoted to his current position as Professor in 2006. His current research involves deciphering the mechanisms that control normal brain functions and how aberrations in these mechanisms causes diseased states such as cancer and neurodegenerative disorders. Dr. Majumder has a strong interest in teaching. In addition to leading a lab with undergraduate, graduate, postdoctoral and clinical fellows, he teaches at the Graduate School of Biomedical Sciences and organizes a biennial course at Cold Spring Harbor Laboratories on Brain Tumors. Dr. Majumder has received many awards including M. D. Anderson Fort Worth Living Legend Faculty Achievement Award, National Brain Tumor Society Chaiken Chair of Research Award, and B*CURED Research Award. Research Interests Mechanisms of normal development and diseased states in mammalian brain The research in my laboratory is focused on (1) deciphering the mechanisms that control normal development, (2) learning how aberrations in these mechanisms produces diseased states, and (3) investigating how such knowledge can be translated into improved patient care. In general, we begin by studying biological mechanisms and then build on the lessons learned from those studies using multiple methods including genomics, bioinformatics, biochemistry, cell biology, and mouse genetics. Our work involves close collaboration between basic scientists and clinicians. One of the first projects in my laboratory focused on advancing understanding of the childhood brain tumor medulloblastoma (MB) as a foundation for patient-specific therapeutic approaches. In the course of our early work, we discovered that the transcriptional repressor REST is aberrantly overexpressed in a subclass of MB tumors and that a unique role of REST in these MB tumors is to block differentiation of the cerebellar stem/progenitor cells. This work was exciting because we, using REST-VP16, and others, using HDAC- and DNMT1-inhibitors, could block REST function. Our work then evolved into an investigation of the mechanisms of stemness in neural stem cells, muscle progenitor cells, embryonic stem cells, and glioblastoma stem cells. Based on our understanding of these mechanisms, in one line of work, we converted muscle progenitor cells into functional neurons before the iPS system was published. Another line of work resolved some of the contradictions in the literature and showed that the REST-mediated regulation of ES cell pluripotency through a microRNA-mediated pathway depends on the cell type (not all ES lines are the same) as well as the culture conditions, indicating how various factors form part of an interconnected regulatory network. In a third line of work, we discovered that REST regulates glioblastoma (GBM) stem cell tumorigenicity by maintaining self-renewal and invasion. Importantly, high levels of REST characterize a class of human GBM patient tumors. Our recent genome-wide analysis followed by biochemical validation indicated that REST performs its functions in GSCs through a microRNA pathway (miR-124, a known REST target, and miR-203, a new target). In addition, using such genome-wide analyses, we discovered a new mechanism (miR-21-Sox2 regulatory axis)-based GBM patient classification with implications for precision medicine. We found that this classification identifies a distinct population of glioblastoma patients with distinguishable phenotypic characteristics and clinical outcomes. In yet another line of work, we generated conditional REST overexpression knockin mice to study REST function in the brain under physiological conditions. While studying the behavior of these mice, we found evidence suggesting that REST affects neurological and neuropsychiatric functions. We are currently using multiple methods to elucidate the role of REST in tumorigenesis and in neurological/neuropsychiatric conditions, and to examine implications for therapy.
KPMG Norway gains operational flexibility with Azure
KPMG Norway is a professional services firm providing audit, tax and advisory services. With Microsoft Azure, they can focus less on running their data centers and more on the value they can bring to their customers. Azure Stack has helped them make internal delivery as simple as possible, and gives them the flexibility needed to onboard larger customers. Additionally, since the GDPR’s inception, restrictions on how privacy data is handled has been a high priority. To address this European data regulation, KPMG Norway depends on Azure to identify the data at-hand, identify any gaps, and use tools to help close them. Watch to learn how Microsoft Azure provided KPMG Norway the ability to gain operational flexibility and regulatory resilience. Visit the full customer story: https://customers.microsoft.com/en-us/story/kpmg-norway-partner-professional-services-azure
Views: 1560 Microsoft Azure
Pyruvate Dehydrogenase Complex Deficiency (PDCD)
This is a story filmed on a boy who mysteriously became sick as a toddler and was found to have an extremely rare mitochondrial disorder named Pyruvate Dehydrogenase Complex Deficiency. Pyruvate Dehydrogenase Complex Deficiency (PDCD) is one of the most common neurodegenerative disorders associated with abnormal mitochondrial metabolism. "PDH deficiency" is an X-linked disease that shows heterogeneous characteristics in both clinical presentation and biochemical abnormality. The "PDH Complex" is a multi-enzyme complex that plays a vital role as a key regulatory step in the central pathways of energy metabolism in the mitochondria. The most commonly seen form of "Pyruvate Dehydrogenase Complex Deficiency" is caused by mutations in the X-linked E1 alpha gene and is approximately equally prevalent in both males and females. However, a greater severity of symptoms tends to affect males more often than heterozygous females. This can be explained by x-inactivation, as females carry one normal and one mutant gene. Cells with a normal allele active can metabolize the lactic acid that is released by the PDH deficient cells. They cannot, however, supply ATP to these cells and, therefore, phenotype depends largely on the nature/severity of the mutation. . JOIN QUIZGROUP PARTNER PROGRAM: http://join.quizgroup.com/ .
Views: 65528 Documentary
MBI Research Highlights: Mechanosensitive Regulation of Spermatheca Contraction
Researchers at the Mechanobiology Institute (MBI), National University of Singapore have identified a novel mechanosensitive regulation of epithelial tube contraction. These findings were published in Current Biology (Pei Yi Tan and Ronen Zaidel-Bar. Transient membrane localization of SPV-1 drives cyclical actomyosin contractions in the C. elegans spermatheca, Current Biology, 19 Dec 2014, doi: 10.1016/j.cub.2014.11.033). For more information on this work visit http://mbi.nus.edu.sg/features/spv-1/ For more information on A/Prof Zaidel-Bar visit http://mbi.nus.edu.sg/ronen-zaidel-bar/
Molecular Biology Laboratory Agricultural Genetics Institute Vien Di truyen Nong Nghiep Tuliem, Hanoi VIETNAM
Views: 200912 congthanhng
Alcohol Regulations Work Better Than Expected, ACA Might Not - HCT News Nov. 20, 2015
Alcohol regulations work better than expected, ACA exchanges might not. This is Healthcare Triage News. Those of you who want to read more can go here: http://theincidentaleconomist.com/wordpress/?p=67962 John Green -- Executive Producer Stan Muller -- Director, Producer Aaron Carroll -- Writer Mark Olsen -- Graphics http://www.twitter.com/aaronecarroll http://www.twitter.com/crashcoursestan http://www.twitter.com/johngreen http://www.twitter.com/olsenvideo And the housekeeping: 1) You can support Healthcare Triage on Patreon: http://vid.io/xqXr Every little bit helps make the show better! 2) Check out our Facebook page: http://goo.gl/LnOq5z 3) We still have merchandise available at http://www.hctmerch.com
Views: 20787 Healthcare Triage
What is blood pressure? | Circulatory system physiology | NCLEX-RN | Khan Academy
Find out what a systolic and diastolic blood pressure mean. Rishi is a pediatric infectious disease physician and works at Khan Academy. Created by Rishi Desai. Watch the next lesson: https://www.khanacademy.org/test-prep/nclex-rn/nclex-rn-circulatory-system/blood-pressure/v/learn-how-a-stethoscope-can-help-determine-blood-pressure?utm_source=YT&utm_medium=Desc&utm_campaign=Nclex-rn Missed the previous lesson? https://www.khanacademy.org/test-prep/nclex-rn/nclex-rn-circulatory-system/rn-circulatory-system/v/thermoregulation-in-the-circulatory-system?utm_source=YT&utm_medium=Desc&utm_campaign=Nclex-rn NCLEX-RN on Khan Academy: A collection of questions from content covered on the NCLEX-RN. These questions are available under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 United States License (available at http://creativecommons.org/licenses/by-nc-sa/3.0/us/). About Khan Academy: Khan Academy offers practice exercises, instructional videos, and a personalized learning dashboard that empower learners to study at their own pace in and outside of the classroom. We tackle math, science, computer programming, history, art history, economics, and more. Our math missions guide learners from kindergarten to calculus using state-of-the-art, adaptive technology that identifies strengths and learning gaps. We've also partnered with institutions like NASA, The Museum of Modern Art, The California Academy of Sciences, and MIT to offer specialized content. For free. For everyone. Forever. #YouCanLearnAnything Subscribe to Khan Academy’s NCLEX-RN channel: https://www.youtube.com/channel/UCDx5cTeADCvKWgF9x_Qjz3g?sub_confirmation=1 Subscribe to Khan Academy: https://www.youtube.com/subscription_center?add_user=khanacademy
Views: 320915 khanacademymedicine
Nava Segev - Regulation and coordination of intra-cellular trafficking pathways
Our research is aimed at understanding how a basic cellular process, trafficking inside cells, is regulated. In the multiple intracellular trafficking pathways, proteins and membranes are transported between intracellular compartments. Individual pathway steps are regulated by molecular switches termed Ypt/Rab GTPases, whose switching depends on upstream activators. Our goal is to elucidate how Ypt/Rab GTPases and their cognate activators regulate individual transport steps and coordinate them in the same pathway and in different pathways. Landmark discoveries about the mechanisms and machinery that underlie intracellular trafficking were made in yeast and shown to pertain to humans. Therefore, we are using yeast as a model system to address these complicated issues, because it allows easy utilization of sophisticated genetic approaches in combination with molecular and cellular methods. Furthermore, the relatively small number of players (e.g., 11 Ypts in yeast versus ~70 Rabs in humans) and the resultant simplified interaction networks make yeast an excellent model for studying the coordination of transportsteps. Our recent findings show that during cell growth, Ypt1 and Ypt31 GTPases together with their activators coordinate transport through the Golgi, the sorting compartment of the secretory pathway. In contrast, under stress, Ypt1 with different activators regulate shuttling of cargo destined for recycling through the autophagy pathway. This study is highly relevant to human health because multiple essential processes, such as secretion of hormones, presentation of receptors on the outer cell membrane, internalization of ligands and receptors, and response to stress, depend on efficient and well-coordinated intracellular trafficking. Therefore, impairment of trafficking affects every system in the human body, including the development and functioning of the brain, heart, and immune system. Human homologs of the yeast trafficking regulators we study were implicated in multiple human illnesses, including cancer and neurodegenerative diseases.

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